The contact owns a 2017 Mercedes-Benz E300. The contact stated while driving approximately 40 MPH, the accelerator pedal was depressed; however, the vehicle hesitated before shifting to a higher gear. The contact stated that the transmission was also slipping out of gear, and the vehicle shifted into LIMP Mode. The contact stated that several unknown warning lights were illuminated. The contact stated that the transmission was not shifting above second gear. The contact had the vehicle towed to a local dealer who diagnosed the vehicle and determined that the transmission control module (TCM) had failed and needed to be replaced. The vehicle was being repaired. The manufacturer was informed of the failure. The contact researched online and related the failure to NHTSA Campaign Number: 17V078000 (Power Train); however, the VIN was not included in the recall. The failure mileage was approximately 100,000.